Annual report pursuant to Section 13 and 15(d)

Summary of Significant Accounting Policies (Tables)

Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2023

Schedule of Property and Equipment Depreciated Using the Straight-Line Method Over the Estimated Useful Life of Each Asset

Property and equipment are stated at cost less accumulated depreciation. Property and equipment are depreciated using the straight-line method over the estimated useful life of each asset as follows:


	Estimated Useful Life
Leasehold improvements	Shorter of life of lease or 10 years
Furniture and fixtures	5 years
Computer equipment	3 years

Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares Outstanding

For the periods presented, the following ordinary shares underlying the options, unvested restricted share units, warrants and the Exchangeable Notes have been excluded from the calculation because they would be anti-dilutive.


	Year ended December 31,
	2023		2022		2021
Options to purchase ordinary shares		1,109,654		355,591		1,068,639
Unvested restricted share units		16,666		128,728		119,017
Warrants		480,186		480,186		480,186
Exchangeable Notes		1,255,451		1,287,660		1,217,386
Total		2,861,957		2,252,165		2,885,228

Schedule of Distribution of Total Operating Expenses by Geographical Area

The distribution of total operating expenses by geographical area was as follows:


	Year ended December 31,
Operating expenses	2023		2022		2021
Ireland	$	41,829	$	22,015	$	15,926
U.S.		5,603		8,332		8,554
Bermuda		36		36		57
Total	$	47,468	$	30,383	$	24,537

Schedule of Distribution of Long-Lived Assets by Geographical Area

The distribution of long-lived assets by geographical area was as follows:


Long lived assets	December 31, 2023		December 31, 2022
Ireland	$	342	$	4,052
U.S.		287		303
Total	$	629	$	4,355