Annual report pursuant to Section 13 and 15(d)

Cover
- Document and Entity Information
Financial Statements
Notes to Financial Statements
Accounting Policies
- Summary of Significant Accounting Policies (Policies)
Notes Tables
Notes Details

Share-Based Compensation - Summary of Number of Options Outstanding and Weighted-average Exercise Price (Details)

v3.22.4

Share-Based Compensation - Summary of Number of Options Outstanding and Weighted-average Exercise Price (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Compensation Related Costs [Abstract]
Number of Shares, Options outstanding Beginning Balance	1,068,639	63,431	76,636
Number of Shares, Granted	197,085	1,028,090	4,322
Number of Shares, Forfeited	(3,333)		(9,260)
Number of Shares, Cancelled	(906,800)
Number of Shares, Expired		(22,882)	(8,267)
Number of Shares, Options outstanding Ending Balance	355,591	1,068,639	63,431	76,636
Number of Shares, Exercisable at December 31, 2020	59,392
Weighted Average Exercise Price, Options outstanding Beginning Balance	$ 30.12	$ 110.40	$ 118.79
Weighted Average Exercise Price, Granted	2.88	27.13	25.36
Weighted Average Exercise Price, Forfeited	6.15		129.07
Weighted Average Exercise Price, Cancelled	33.16
Weighted Average Exercise Price, Expired		118.49	122.83
Weighted Average Exercise Price, Options outstanding Ending Balance	7.49	$ 30.12	$ 110.40	$ 118.79
Weighted Average Exercise Price, Exercisable at December 31, 2020	$ 22.21
Weighted Average Remaining Contractual Life in Years, Options outstanding	9 years 1 month 13 days	9 years 5 months 1 day	5 years 4 months 28 days	8 years 7 months 2 days
Weighted Average Remaining Contractual Life in Years, Exercisable at December 31, 2019	8 years 1 month 2 days
Aggregate Intrinsic Value, Options outstanding			$ 254
Aggregate Intrinsic Value, Options outstanding				$ 254

- Definition

Share-based compensation arrangement by share-based payment award, options, cancelled in period.

+ References

No definition available.

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- Definition

Share-based compensation arrangements by share-based payment award, options, cancelled in period, weighted average exercise price.

+ References

No definition available.

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- References

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- Definition

The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

+ References

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- Definition

The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan.

+ References

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- Definition

Number of options or other stock instruments for which the right to exercise has lapsed under the terms of the plan agreements.

+ References

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- Definition

The number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan.

+ References

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- Definition

Gross number of share options (or share units) granted during the period.

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- Definition

Amount by which the current fair value of the underlying stock exceeds the exercise price of options outstanding.

+ References

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
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-Paragraph 2
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- Definition

Number of options outstanding, including both vested and non-vested options.

+ References

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
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- Definition

Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.

+ References

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- Definition

Weighted average price at which grantees could have acquired the underlying shares with respect to stock options of the plan that expired.

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- Definition

Weighted average price at which grantees could have acquired the underlying shares with respect to stock options that were terminated.

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- Definition

Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

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- Definition

Weighted average remaining contractual term for vested portions of options outstanding and currently exercisable or convertible, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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- Definition

Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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