Annual report pursuant to Section 13 and 15(d)

Share-Based Compensation - Summary of Stock Option Activity (Details)

v3.22.4
Share-Based Compensation - Summary of Stock Option Activity (Details) - shares
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Number of Shares, Options outstanding Beginning Balance 1,068,639 63,431 76,636
Number of Shares, Granted 197,085 1,028,090 4,322
Number of Shares, Forfeited (3,333)   (9,260)
Number of Shares, Cancelled (906,800)    
Number of Shares, Expired   (22,882) (8,267)
Number of Shares, Options outstanding Ending Balance 355,591 1,068,639 63,431
2015 Plan and 2018 Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Number of Shares, Options outstanding Beginning Balance 948,639 63,431 76,636
Number of Shares, Granted 190,753 908,090 4,322
Number of Shares, Forfeited     (9,260)
Number of Shares, Cancelled (906,800)    
Number of Shares, Expired   (22,882) (8,267)
Number of Shares, Options outstanding Ending Balance 232,592 948,639 63,431
Two Thousand Twenty One Inducement Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Number of Shares, Options outstanding Beginning Balance 120,000    
Number of Shares, Granted 6,332 120,000  
Number of Shares, Forfeited (3,333)    
Number of Shares, Options outstanding Ending Balance 122,999 120,000  
2015 Plan, 2018 Plan and 2021 Inducement Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Number of Shares, Options outstanding Beginning Balance 1,068,639 63,431  
Number of Shares, Granted 197,085 1,028,090 4,322
Number of Shares, Forfeited (3,333)   (9,260)
Number of Shares, Cancelled (906,800)    
Number of Shares, Expired   (22,882) (8,267)
Number of Shares, Options outstanding Ending Balance 355,591 1,068,639 63,431