Annual report pursuant to Section 13 and 15(d)

Share-Based Compensation - Schedule of Assumptions Used to Determine Grant Date Fair Value of Employee and Director Options Granted (Details)

v3.22.4
Share-Based Compensation - Schedule of Assumptions Used to Determine Grant Date Fair Value of Employee and Director Options Granted (Details) - $ / shares
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Volatility, minimum 100.00% 120.00% 90.30%
Volatility, maximum 130.00% 140.00% 99.50%
Dividend rate 0.00% 0.00% 0.00%
Risk-free interest rate, minimum 1.90% 0.90% 0.18%
Risk-free interest rate, maximum 3.96% 1.42% 0.78%
Minimum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term in years 5 years 6 months 5 years 6 months 5 years 6 months
Share price $ 0.81 $ 0.48 $ 1.68
Fair value of option on grant date $ 0.64 $ 0.45 $ 1.27
Maximum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term in years 6 years 3 months 6 years 3 months 6 years 3 months
Share price $ 6.72 $ 2.01 $ 2.03
Fair value of option on grant date $ 5.95 $ 1.75 $ 1.52