Annual report pursuant to Section 13 and 15(d)

Quarterly Financial Data (Unaudited) - Schedule of Unaudited Quarterly Financial Data (Details)

v3.20.1
Quarterly Financial Data (Unaudited) - Schedule of Unaudited Quarterly Financial Data (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract]                      
Revenue       $ 37 $ 239 $ 254 $ 185 $ 191 $ 37 $ 869 $ 508
Total operating expenses $ (23,178) $ (30,999) $ (27,378) (20,503) (24,183) (25,240) (15,611) (12,394) (102,058) (77,428) (29,963)
Net loss (23,641) (31,271) (27,638) (20,580) (24,258) (24,905) (15,747) (12,146) (103,130) (77,056) (29,406)
Net loss attributable to ordinary shareholders $ (23,641) $ (31,271) $ (27,638) $ (20,580) $ (24,258) $ (24,905) $ (15,747) $ (12,146) $ (103,130) $ (77,056) $ (29,406)
Net loss per share attributable to ordinary shareholders – basic and diluted $ (1.59) $ (2.15) $ (1.93) $ (1.44) $ (1.72) $ (1.77) $ (2.22) $ (61.36) $ (7.10) $ (8.82) $ (170.84)
Weighted average ordinary shares outstanding – basic and diluted 14,866,838 14,571,278 14,340,231 14,290,437 14,108,604 14,034,631 7,085,655 197,949 14,518,036 8,734,109 172,130