Annual report pursuant to Section 13 and 15(d)

Income Taxes - Summary of Effective Income Tax Rate (Detail)

v3.19.1
Income Taxes - Summary of Effective Income Tax Rate (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Income Tax [Line Items]      
Impact of U.S. tax rate, Percentage (0.11%) (0.80%) 0.10%
Impact of valuation allowance, Percentage (11.42%) (13.64%) (12.80%)
Research and development tax credit, Percentage 0.45% 0.76%  
Other, net, Percentage (2.03%) (0.36%) (0.65%)
Effective tax rate, Percentage (0.61%) (1.54%) (0.85%)
Statutory rate, Amount $ (9,573) $ (3,620) $ (1,669)
Impact of U.S. tax rate, Amount 81 232 (13)
Impact of valuation allowance, Amount 8,749 3,949 1,708
Research and development tax credit, Amount (341) (220)  
Other, net, Amount 1,557 103 87
Income Tax Provision $ 472 $ 444 $ 113
Ireland      
Income Tax [Line Items]      
Statutory rate, Percentage 12.50% 12.50% 12.50%