Annual report pursuant to Section 13 and 15(d)

Share-Based Compensation - Schedule of Assumptions Used to Determine Grant Date Fair Value of Employee and Director Options Granted (Details)

v3.22.1
Share-Based Compensation - Schedule of Assumptions Used to Determine Grant Date Fair Value of Employee and Director Options Granted (Details) - $ / shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Volatility, minimum 120.00% 90.30% 68.90%
Volatility, maximum 140.00% 99.50% 74.50%
Dividend rate 0.00% 0.00% 0.00%
Risk-free interest rate, minimum 0.90% 0.18% 1.73%
Risk-free interest rate, maximum 1.42% 0.78% 2.57%
Minimum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term in years 5 years 6 months 5 years 6 months 5 years 6 months
Share price $ 0.48 $ 1.68 $ 3.55
Fair value of option on grant date $ 0.45 $ 1.27 $ 2.37
Maximum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Expected term in years 6 years 3 months 6 years 3 months 6 years 3 months
Share price $ 2.01 $ 2.03 $ 6.80
Fair value of option on grant date $ 1.75 $ 1.52 $ 4.41