Quarterly report pursuant to Section 13 or 15(d)

Consolidated Statements of Cash flows (Unaudited)

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Consolidated Statements of Cash flows (Unaudited) - USD ($)
$ in Thousands
 6 Months Ended 12 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2017
Cash flows from operating activities:      
Net loss $ (27,893) $ (12,117)  
Adjustments to reconcile net loss to cash used in operating activities:      
Depreciation 64 14 $ 65
Share-based compensation expense 404 180  
Non-cash (loss) / gain on short term investments (62) 20  
Interest on short-term investments (71) (97)  
Amortization of debt discount and deferred financing costs 138    
Other 245    
Changes in operating assets and liabilities:      
Prepaid expenses and other current assets (1,563) (3,165)  
Other assets (1,065) (584)  
Accounts payable 5,014 624  
Accrued expenses 94 (242)  
Income taxes 60 239  
Other liabilities 65 84  
Net cash used in operating activities (24,570) (15,044)  
Cash flows from investing activities:      
Purchases of property and equipment (53) (612)  
Purchases of short-term investments (53,727) (33,785)  
Proceeds from sale of short-term investments 34,150    
Net cash used in investing activities (19,630) (34,397)  
Cash flows from financing activities:      
Proceeds from issuance of debt, net of debt issuance costs 14,507    
Proceeds from issuance of ordinary shares, net of issuance costs 74,155    
Net cash provided by financing activities 120,835 45,867  
Effect of exchange rates on cash and cash equivalents (99)    
Net increase / (decrease) in cash, cash equivalents and restricted cash 76,536 (3,574)  
Cash, cash equivalents and restricted cash, at beginning of period 8,485 24,809 24,809
Cash, cash equivalents and restricted cash, at end of period 85,021 21,235 $ 8,485
Series B Convertible Preferred Shares      
Cash flows from financing activities:      
Proceeds from issuance of Series B convertible preferred shares $ 32,173 $ 45,867