Quarterly report pursuant to Section 13 or 15(d)

Summary of Significant Accounting Policies - Schedule of Distribution of Total Operating Expenses by Geographical Area (Details)

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Summary of Significant Accounting Policies - Schedule of Distribution of Total Operating Expenses by Geographical Area (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Segment Reporting Information [Line Items]        
Operating expenses $ 15,611 $ 6,413 $ 28,005 $ 11,955
Ireland        
Segment Reporting Information [Line Items]        
Operating expenses 12,811 5,205 22,775 9,674
U.S.        
Segment Reporting Information [Line Items]        
Operating expenses $ 2,800 $ 1,208 $ 5,230 $ 2,281