Quarterly report pursuant to Section 13 or 15(d)

Summary of Significant Accounting Policies (Tables)

Summary of Significant Accounting Policies (Tables)

3 Months Ended

Mar. 31, 2023

Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares Outstanding

For the periods presented, the following ordinary shares underlying the options, unvested restricted share units, warrants and the Exchangeable Notes have been excluded from the calculation because they would be anti-dilutive.


	Three Months Ended
	March 31, 2023		March 31, 2022
Options to purchase ordinary shares		1,213,091		1,081,800
Unvested restricted share units		89,439		82,434
Warrants		480,186		480,186
Exchangeable Notes		1,352,340		1,234,962
Total		3,135,056		2,879,382

Schedule of Distribution of Total Operating Expenses by Geographical Area

The distribution of total operating expenses by geographical area was as follows:


	Three Months Ended March 31,
Operating expenses	2023		2022
Ireland	$	7,068	$	4,549
U.S.		1,440		2,811
Bermuda		22		13
Total	$	8,530	$	7,373

Schedule of Distribution of Long-Lived Assets by Geographical Area

The distribution of long-lived assets by geographical area was as follows:


Long-lived assets	March 31, 2023		December 31, 2022
Ireland	$	3,565	$	4,052
U.S.		275		303
Total	$	3,840	$	4,355