Quarterly report pursuant to Section 13 or 15(d)

Share-Based Compensation - Additional Information (Details)

Share-Based Compensation - Additional Information (Details) - USD ($) $ in Thousands									3 Months Ended		9 Months Ended
	Jul. 07, 2022	Nov. 24, 2021	Jun. 22, 2021	Jun. 10, 2020	Feb. 14, 2020	Dec. 31, 2018	Dec. 05, 2018	Nov. 18, 2015	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021	Jun. 23, 2021	Mar. 14, 2018	May 18, 2017
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of Shares, Granted											167,960
Cancellation of share options expense									$ 17,350		$ 17,350
Number of shares, cancelled											(906,800)
Employee Stock Options
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unvested employee options outstanding									301,623	915,504	301,623	915,504
Expense recognized									$ 135	$ 1,663	$ 3,498	$ 2,104
Unamortized compensation expense share options									1,094	22,385	$ 1,094	$ 22,385
Vesting period											1 year 10 months 17 days	3 years 8 months 4 days
Risk-free interest rate based on estimate of U.S. treasury yield											7 years
Restricted Share Units (RSUs)
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Expense recognized									287	304	$ 803	$ 668
Number of shares, granted/awarded											57,432
Unamortized stock compensation expense									$ 712		$ 712
Stock-based compensation expense, expected weighted average period for recognition											1 year 3 months 7 days	1 year 4 months 6 days
Unamortized compensation expense										1,467		$ 1,467
Restricted Share Units (RSUs) \| Director
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Vesting period											1 year
Performance RSUs
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Expense recognized										455		$ 420
Number of shares, granted/awarded									0			0
Options and Restricted Share Units and Performance Restricted Share Units
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Vesting period											1 year 8 months 15 days	3 years 6 months 29 days
Unamortized compensation expense									$ 1,806	$ 23,852	$ 1,806	$ 23,852
2015 Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized								14,895
Number of ordinary shares available for issuance															29,535
Increase in number of ordinary shares available for issuance								14,640
2018 Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized													1,295,819	67,897
Increase in number of ordinary shares available to be granted, percentage					4.00%		4.00%
Increase in number of ordinary shares available to be granted			1,000,000	150,000	39,650	38,272
2018 Plan \| Employees and Directors
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares, granted/awarded											57,432
2018 Plan \| Employees and Directors
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of Shares, Granted											161,628	908,094
2018 Plan \| Restricted Share Units (RSUs) \| Employees and Directors
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares, granted/awarded												89,688
2018 Plan \| Restricted Share Units (RSUs) \| Employees \| Minimum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Vesting period											2 years
2018 Plan \| Restricted Share Units (RSUs) \| Employees \| Maximum
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Vesting period											4 years
2021 Inducement Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Increase in number of ordinary shares available to be granted		333,333
2021 Inducement Plan \| Employees and Directors
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of Shares, Granted											6,332	0
2015 Plan, 2018 Plan and 2021 Inducement Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of Shares, Granted											167,960
2015 Plan, 2018 Plan and 2021 Inducement Plan \| Employee Stock Options
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Vesting period											4 years
Vesting rights											The vesting requirement is conditioned upon a grantee’s continued service with the Company during the vesting period. Once vested, all awards are exercisable from the date of grant until they expire. The option grants are non-transferable. Vested options generally remain exercisable for 90 days subsequent to the termination of the option holder’s service with the Company. In the event of an option holder’s disability or death while employed by or providing service to the Company, the exercisable period extends to twelve months or eighteen months, respectively.
Share option granted term											10 years
2015 Plan, 2018 Plan and 2021 Inducement Plan \| Restricted Share Units (RSUs)
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares, granted/awarded											57,432
Amended and Restated 2018 Equity Incentive Plan
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares, cancelled	906,800
Amended and Restated 2018 Equity Incentive Plan \| Employee Stock Options
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Cancellation of share options expense									$ 17,350		$ 17,350