Quarterly report pursuant to Section 13 or 15(d)

Summary of Significant Accounting Policies (Tables)

Summary of Significant Accounting Policies (Tables)

9 Months Ended

Sep. 30, 2022

Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares Outstanding

For the periods presented, the following ordinary shares underlying the options, unvested restricted share units, unvested performance restricted share units, warrants and the Exchangeable Notes have been excluded from the calculation because they would be anti-dilutive.


	Three Months Ended				Nine Months Ended
	September 30, 2022		September 30, 2021		September 30, 2022		September 30, 2021
Options to purchase ordinary shares		329,799		—		329,799		951,426
Unvested restricted share units		128,096		—		128,096		85,684
Unvested performance restricted share units		—		—		—		1,733
Warrants		480,186		—		480,186		480,186
Exchangeable Notes		1,270,094		—		1,270,094		1,199,819
Total		2,208,175		—		2,208,175		2,718,848

Schedule of Distribution of Total Operating Expenses by Geographical Area

The distribution of total operating expenses by geographical area was as follows:


	Three Months Ended September 30,				Nine Months Ended September 30,
Operating expenses	2022		2021		2022		2021
Ireland	$	5,675	$	3,056	$	15,302	$	11,166
U.S.		1,352		1,817		7,129		6,495
Bermuda		7		1		26		47
Total	$	7,034	$	4,874	$	22,457	$	17,708

Schedule of Distribution of Long-Lived Assets by Geographical Area

The distribution of long-lived assets by geographical area was as follows:


Long-lived assets	September 30, 2022		December 31, 2021
Ireland	$	4,572	$	7,601
U.S.		297		578
Total	$	4,869	$	8,179