Quarterly report pursuant to Section 13 or 15(d)

Consolidated Statements of Cash flows (Unaudited)

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Consolidated Statements of Cash flows (Unaudited) - USD ($)
$ in Thousands
 9 Months Ended 12 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Cash flows from operating activities:      
Net loss $ (52,799) $ (20,288)  
Adjustments to reconcile net loss to cash used in operating activities:      
Depreciation 99 36 $ 65
Share-based compensation expense 878 280  
(Gain) / loss on short term investments (128) (13)  
Non-cash (gain) / loss on short term investments (315) 37  
Interest on short-term investments (34) (143)  
Amortization of debt discount and deferred financing costs 174    
Other 304    
Changes in operating assets and liabilities:      
Prepaid expenses and other current assets 165 (3,124)  
Other assets (1,406) (857)  
Accounts payable (449) 2,758  
Accrued expenses 1,349 700  
Income taxes (18) 59  
Other liabilities 115 74  
Net cash used in operating activities (52,065) (20,481)  
Cash flows from investing activities:      
Purchases of property and equipment (69) (765)  
Purchases of short-term investments (88,735) (43,268)  
Proceeds from sale of short-term investments 51,400 6,000  
Net cash used in investing activities (37,404) (38,033)  
Cash flows from financing activities:      
Proceeds from issuance of debt, net of debt issuance costs 14,507    
Proceeds from issuance of ordinary shares, net of issuance costs 74,155    
Net cash provided by financing activities 120,835 45,867  
Effect of exchange rates on cash and cash equivalents (133)    
Net increase / (decrease) in cash, cash equivalents and restricted cash 31,233 (12,647)  
Cash, cash equivalents and restricted cash, at beginning of period 8,485 24,809 24,809
Cash, cash equivalents and restricted cash, at end of period 39,718 12,162 $ 8,485
Series B Convertible Preferred Shares      
Cash flows from financing activities:      
Proceeds from issuance of Series B convertible preferred shares $ 32,173 $ 45,867