Commitment and Contingencies - Additional Information (Details) € in Thousands	Sep. 30, 2019 USD ($)	Dec. 31, 2018 USD ($)	Jun. 30, 2018 USD ($)	Jun. 30, 2018 EUR (€)	Jun. 30, 2016 USD ($)	Jun. 30, 2016 EUR (€)	Nov. 18, 2015 USD ($)
Other Commitments [Line Items]
Purchase obligation	$ 164,000	$ 1,604,000			$ 2,727,000	€ 2,500
Pfizer License Agreement \| Minimum
Other Commitments [Line Items]
Potential future regulatory milestone and sales milestone payments upon achievement of net sales							$ 250,000,000
Pfizer License Agreement \| Maximum
Other Commitments [Line Items]
Potential future regulatory milestone and sales milestone payments upon achievement of net sales							$ 1,000,000,000
Supplemental Agreement
Other Commitments [Line Items]
Purchase obligation			$ 2,236,000	€ 2,050