Quarterly report pursuant to Section 13 or 15(d)

Summary of Significant Accounting Policies - Schedule of Distribution of Total Operating Expenses by Geographical Area (Details)

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Summary of Significant Accounting Policies - Schedule of Distribution of Total Operating Expenses by Geographical Area (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Segment Reporting Information [Line Items]        
Operating expenses $ 30,999 $ 25,240 $ 78,880 $ 53,246
Ireland        
Segment Reporting Information [Line Items]        
Operating expenses 28,309 22,444 70,006 45,219
U.S.        
Segment Reporting Information [Line Items]        
Operating expenses $ 2,690 $ 2,796 $ 8,874 $ 8,027