Quarterly report pursuant to Section 13 or 15(d)

Commitment and Contingencies - Additional Information (Details)

v3.19.2
Commitment and Contingencies - Additional Information (Details) - USD ($)
Jun. 30, 2019
Dec. 31, 2018
Jun. 30, 2018
Jun. 30, 2016
Nov. 18, 2015
Other Commitments [Line Items]          
Purchase obligation $ 1,478,000 $ 1,604,000   $ 2,842,000  
Pfizer License Agreement | Minimum          
Other Commitments [Line Items]          
Potential future regulatory milestone and sales milestone payments upon achievement of net sales         $ 250,000,000
Pfizer License Agreement | Maximum          
Other Commitments [Line Items]          
Potential future regulatory milestone and sales milestone payments upon achievement of net sales         $ 1,000,000,000
Supplemental Agreement          
Other Commitments [Line Items]          
Purchase obligation     $ 2,331,000