Quarterly report pursuant to Section 13 or 15(d)

Summary of Significant Accounting Policies - Schedule of Distribution of Total Operating Expenses by Geographical Area (Details)

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Summary of Significant Accounting Policies - Schedule of Distribution of Total Operating Expenses by Geographical Area (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Segment Reporting Information [Line Items]        
Operating expenses $ 27,378 $ 15,611 $ 47,881 $ 28,005
Ireland        
Segment Reporting Information [Line Items]        
Operating expenses 24,261 12,811 41,697 22,775
U.S.        
Segment Reporting Information [Line Items]        
Operating expenses $ 3,117 $ 2,800 $ 6,184 $ 5,230