Quarterly report pursuant to Section 13 or 15(d)

Shareholders' Equity - Reconciliation of Beginning and Ending Balances in Shareholders' Equity (Details)

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Shareholders' Equity - Reconciliation of Beginning and Ending Balances in Shareholders' Equity (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Dec. 31, 2018
Class Of Stock [Line Items]      
Shareholders' equity, Beginning Balance $ 71,622 $ 39,494 $ 39,494
Exercise of share options 48    
Share-based compensation expense 540 149  
Net loss (20,580) (12,146) (77,056)
Shareholders' equity, Ending Balance $ 51,630 59,656 $ 71,622
Series B Convertible Preferred Shares      
Class Of Stock [Line Items]      
Issuance of Series B convertible preferred shares, net   $ 32,159