Quarterly report pursuant to Section 13 or 15(d)

Share-Based Compensation (Tables)

Share-Based Compensation (Tables)

3 Months Ended

Mar. 31, 2019

Schedule of Assumptions Used to Determine Grant Date Fair Value of Employee and Director Options Granted

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Summary of Restricted Ordinary Shares Activity

The following table summarizes restricted ordinary shares activity for the three months ended March 31, 2019:

	Number of Shares			Weighted Average Grant Date Fair Value per Share
Unvested at December 31, 2018		86,068		$	3.14
Granted		—
Vested		(25,818	)	$	3.14
Forfeited		—
Unvested at March 31, 2019 (unaudited)		60,250		$	3.14

Summary of Number of Options Outstanding and Weighted-average Exercise Price

The following table summarizes the number of options outstanding and the weighted-average exercise price:

	Number of Shares			Weighted Average Exercise Price		Weighted Average Remaining Contractual Life in Years		Aggregate Intrinsic Value (in thousands)
Options outstanding December 31, 2018		665,219		$	9.31		8.93	395
Granted		442,500			5.82
Exercised		(15,395	)		3.16
Forfeited		(1,086	)		9.44
Options outstanding March 31, 2019		1,091,238		$	7.98		9.27		1,956
Exercisable at March 31, 2019 (unaudited)		106,325		$	4.59		8.25		425

Summary of Number of RSUs Granted and Weighted-average Grant Date Fair Value of RSUs

The table below shows the number of RSUs granted covering an equal number of our ordinary shares and the weighted-average grant date fair value of the RSUs granted:

	Number of Shares		Weighted Average Grant Date Fair Value per Share
RSUs outstanding December 31, 2018		36,924	$	13.00
Granted		—
Shares vested		—
Forfeited		—
RSUs outstanding March 31, 2019		36,924	$	13.00

Summary of Share-based Compensation Expense

The Company’s share-based compensation expense was classified in the condensed consolidated statements of operations and comprehensive loss as follows:

	Three Months Ended March 31,
	2019		2018
Research and development expense	$	163	$	71
General and administrative expense		377		78

Performance RSU [Member}

Summary of Number of RSUs Granted and Weighted-average Grant Date Fair Value of RSUs

The table below shows the number of Performance RSUs granted covering an equal number of our ordinary shares and the weighted-average grant date fair value of the Performance RSUs granted:

	Number of Shares		Weighted Average Grant Date Fair Value per Share
Performance RSUs outstanding December 31, 2018		—
Granted		50,000	$	8.21
Shares vested		—
Forfeited		—
Performance RSUs outstanding March 31, 2019		50,000	$	8.21