Quarterly report pursuant to Section 13 or 15(d)

Shareholders' Equity - Additional Information (Details)

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Shareholders' Equity - Additional Information (Details)
1 Months Ended 6 Months Ended 41 Months Ended
Oct. 17, 2022
USD ($)
Oct. 07, 2022
USD ($)
$ / shares
Feb. 12, 2021
$ / shares
shares
Feb. 10, 2021
$ / shares
shares
Feb. 08, 2021
$ / shares
shares
Oct. 31, 2020
$ / shares
shares
Oct. 27, 2020
$ / shares
shares
Jul. 02, 2020
$ / shares
shares
Jun. 05, 2020
$ / shares
shares
Jun. 03, 2020
$ / shares
shares
Apr. 27, 2018
$ / shares
shares
Jun. 30, 2020
$ / shares
shares
Jun. 30, 2024
USD ($)
Vote
$ / shares
shares
Jun. 30, 2023
USD ($)
$ / shares
Jun. 30, 2024
USD ($)
$ / shares
shares
Dec. 31, 2023
$ / shares
shares
May 03, 2023
$ / shares
shares
Class Of Stock [Line Items]                                  
Increase to authorized ordinary shares                                 60,000,000
Ordinary shares, par value | $ / shares                         $ 0.01 $ 0.01 $ 0.01 $ 0.01 $ 0.01
Ordinary shares, shares authorized                         80,000,000   80,000,000 80,000,000  
Number of vote per common share | Vote                         1        
Common stock shares with preemptive rights                         60,000,000   60,000,000    
Number of ordinary shares not have preemptive or other subscription rights                         20,000,000   20,000,000    
Common stock rights and preferences                         The holders of ordinary shares currently have preemptive rights over 60,000,000 ordinary shares and no preemptive or other subscription rights over 20,000,000 ordinary shares. There are no redemption or sinking fund provisions with respect to the authorized ordinary shares.        
Authorized amount for sale of stock | $ $ 100,000,000                                
Ordinary shares, shares issued                         16,584,029   16,584,029 13,499,003  
Proceeds from registered direct offerings, net of transaction costs | $                         $ 7,384,000 $ 435,000      
Aggregate principal amount of exchangeable notes | $                             $ 40,691,000    
Undesignated preferred shares, par value | $ / shares                         $ 0.01   $ 0.01 $ 0.01  
Undesignated preferred shares, authorized                         100,000,000   100,000,000 100,000,000  
Undesignated preferred shares issued                         0   0 0  
Sales Agreement With H.C. Wainwright                                  
Class Of Stock [Line Items]                                  
Ordinary shares, par value | $ / shares   $ 0.01                              
Maximum | Sales Agreement With H.C. Wainwright                                  
Class Of Stock [Line Items]                                  
May offer and sell ordinary shares for aggregate gross sales proceeds | $   $ 16,000,000                              
Private Placement | Securities Purchase Agreement                                  
Class Of Stock [Line Items]                                  
Number of warrants to purchase ordinary shares                 13,868                
Warrants to purchase ordinary shares, exercise price | $ / shares                 $ 31.5465 $ 24.3              
Warrants expiry date                 Jun. 03, 2025 Dec. 05, 2025              
Warrants exercisable date                 Jun. 03, 2020                
Percentage of ordinary shares issued to purchase warrants                 7.00%                
Private Placement | Securities Purchase Agreement | Maximum                                  
Class Of Stock [Line Items]                                  
Number of warrants to purchase ordinary shares                   99,057              
Private Placement | June 30 SPA                                  
Class Of Stock [Line Items]                                  
Number of warrants to purchase ordinary shares               15,739                  
Warrants to purchase ordinary shares, exercise price | $ / shares               $ 27.7965       $ 21.3          
Warrants expiry date               Jun. 30, 2025       Jan. 02, 2026          
Percentage of ordinary shares issued to purchase warrants               7.00%                  
Proceeds from exercise of warrants related to registered direct offering | $                         $ 1,796,000        
Warrants exercised                         84,317   84,317    
Private Placement | June 30 SPA | Maximum                                  
Class Of Stock [Line Items]                                  
Number of warrants to purchase ordinary shares                       112,422          
October Offering                                  
Class Of Stock [Line Items]                                  
Proceeds from registered direct offerings, net of transaction costs | $                         $ 13,885,000        
Number of warrants to purchase ordinary shares           125,641                      
Number of warrants exercised for ordinary shares                         1,392,701   1,392,701    
Warrants to purchase ordinary shares, exercise price | $ / shares           $ 12.1875 $ 9.75                    
Warrants expiry date           Oct. 22, 2025 Oct. 27, 2025                    
Percentage of ordinary shares issued to purchase warrants           7.00%                      
October Offering | Maximum                                  
Class Of Stock [Line Items]                                  
Number of warrants to purchase ordinary shares             1,346,153                    
February Underwritten Offering                                  
Class Of Stock [Line Items]                                  
Offering closing date       Feb. 10, 2021 Feb. 08, 2021                        
Additional ordinary shares that can be purchased by underwriter       347,826                          
Number of warrants exercised for ordinary shares                         25,333   25,333    
Warrants to purchase ordinary shares, exercise price | $ / shares       $ 21.5625 $ 21.5625                        
Warrants expiry date       Feb. 03, 2026 Feb. 03, 2026                        
Percentage of ordinary shares issued to purchase warrants       7.00% 7.00%                        
Proceeds from warrants connected to registered direct offerings | $                         $ 546,000        
February Underwritten Offering | Maximum                                  
Class Of Stock [Line Items]                                  
Number of warrants to purchase ordinary shares       24,347 162,318                        
At-the-market agreement                                  
Class Of Stock [Line Items]                                  
Number of ordinary shares sold                         3,055,882        
Offering price per share | $ / shares                         $ 2.49   $ 2.49    
Proceeds from registered direct offerings, net of transaction costs | $                         $ 7,400,000        
February Registered Direct Offering                                  
Class Of Stock [Line Items]                                  
Offering closing date     Feb. 12, 2021                            
Number of warrants to purchase ordinary shares     81,666                            
Warrants to purchase ordinary shares, exercise price | $ / shares     $ 37.5                            
Warrants expiry date     Feb. 09, 2026                            
Percentage of ordinary shares issued to purchase warrants     7.00%                            
Warrants to Purchase 19,890 Ordinary Shares | Silicon Valley Bank and Life Sciences Fund II LLC                                  
Class Of Stock [Line Items]                                  
Warrants expiry date                     Apr. 27, 2028            
Series B Convertible Preferred Shares | Silicon Valley Bank and Life Sciences Fund II LLC                                  
Class Of Stock [Line Items]                                  
Number of warrants to purchase ordinary shares                     19,890            
Warrants to purchase ordinary shares, exercise price | $ / shares                     $ 282.75            
Undesignated Preferred Shares                                  
Class Of Stock [Line Items]                                  
Undesignated preferred shares, par value | $ / shares                         $ 0.01   $ 0.01    
Undesignated preferred shares, authorized                         100,000,000   100,000,000    
Designated Preferred Shares                                  
Class Of Stock [Line Items]                                  
Undesignated preferred shares issued                         0   0 0  
Ordinary Shares | Silicon Valley Bank and Life Sciences Fund II LLC                                  
Class Of Stock [Line Items]                                  
Number of warrants to purchase ordinary shares                     1,326            
Exchangeable Notes                                  
Class Of Stock [Line Items]                                  
Ordinary shares, shares issued                         3,760,155   3,760,155    
Aggregate principal amount of exchangeable notes | $                             $ 40,691,000    
Aggregate principal amount | $                         $ 11,117,000   11,117,000    
Exchangeable Notes | Private Placement                                  
Class Of Stock [Line Items]                                  
Aggregate principal amount of exchangeable notes | $                             $ 40,691,000