Quarterly report pursuant to Section 13 or 15(d)

Summary of Significant Accounting Policies (Tables)

Summary of Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2021

Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares Outstanding

For the periods presented, the following ordinary shares underlying the options, unvested restricted share units, unvested performance restricted share units, warrants and the Exchangeable Notes have been excluded from the calculation because they would be anti-dilutive.

	Three months ended				Six Months Ended
	June 30, 2021		June 30, 2020		June 30, 2021		June 30, 2020
Options to purchase ordinary shares		—		1,168,891		14,065,145		1,168,891
Unvested restricted share units		—		14,258		1,315,328		14,258
Unvested performance restricted share units		—		1,095,000		407,000		1,095,000
Warrants		—		1,713,799		7,202,878		1,713,799
Exchangeable Notes		—		53,087,634		17,733,806		53,087,634
Total		—		57,079,582		40,724,157		57,079,582

Schedule of Distribution of Total Operating Expenses by Geographical Area

The distribution of total operating expenses by geographical area was as follows:

	Three Months Ended June 30,				Six Months Ended June 30,
Operating expenses	2021		2020		2021		2020
Ireland	$	4,192	$	5,641	$	8,110	$	15,072
U.S.		2,794		2,612		4,678		6,075
Bermuda		1		—		46		—
Total	$	6,987	$	8,253	$	12,834	$	21,147

Schedule of Distribution of Long-Lived Assets by Geographical Area

The distribution of long-lived assets by geographical area was as follows:

Long-lived assets	June 30, 2021		December 31, 2020
Ireland	$	7,689	$	8,101
U.S.		1,894		2,971
Total	$	9,583	$	11,072