Quarterly report pursuant to Section 13 or 15(d)

Summary of Significant Accounting Policies (Tables)

Summary of Significant Accounting Policies (Tables)

3 Months Ended

Mar. 31, 2020

Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares Outstanding

For the periods presented, the following ordinary shares underlying the options, unvested restricted ordinary shares, unvested restricted share units, unvested performance restricted share units and the warrants have been excluded from the calculation because they would be anti-dilutive.

	Three Months Ended
	March 31, 2020		March 31, 2019
Options to purchase ordinary shares		1,133,208		1,091,238
Unvested restricted ordinary shares		-		60,250
Unvested restricted share units		25,664		36,924
Unvested performance restricted share units		1,127,000		50,000
Warrants		19,890		19,890
Total		2,305,762		1,258,302

Schedule of Distribution of Total Operating Expenses by Geographical Area

The distribution of total operating expenses by geographical area was as follows:

	Three Months Ended March 31,
Operating expenses	2020		2019
Ireland	$	9,431	$	17,436
U.S.		3,463		3,067
Total	$	12,894	$	20,503

Schedule of Distribution of Long-Lived Assets by Geographical Area

The distribution of long-lived assets by geographical area was as follows:

Long-lived assets	March 31, 2020		December 31, 2019
Ireland	$	10,865	$	10,936
U.S.		2,970		3,037
Total	$	13,835	$	13,973