Commitments and Contingencies - Additional Information (Details)				6 Months Ended
	Oct. 28, 2024	Sep. 08, 2020 Debtinstrument	Jan. 21, 2020 Debtinstrument	Jun. 30, 2025 USD ($) UsdRln	Nov. 18, 2015 USD ($)
Royalty-Linked Notes
Other Commitments [Line Items]
Debt instrument outstanding portion \| UsdRln				0.04
Debt instrument maturity date				Dec. 31, 2045
Debt instrument price per unit				$ 160.00
Debt instrument, aggregate potential payment capped rate				4,000
Royalty-Linked Notes \| Private Placement
Other Commitments [Line Items]
Number of debt instruments issued \| Debtinstrument			2,579,400
Royalty-Linked Notes \| 2020 Rights Offering
Other Commitments [Line Items]
Number of debt instruments issued \| Debtinstrument		11,000
Pfizer License Agreement
Other Commitments [Line Items]
Regulatory milestone payments upon approval of product					$ 20,000,000
Regulatory and sales milestone deferred payment period	2 years
Pfizer License Agreement \| Minimum
Other Commitments [Line Items]
Regulatory and sales milestone payments upon achievement of net sales					250,000,000
Pfizer License Agreement \| Maximum
Other Commitments [Line Items]
Regulatory and sales milestone payments upon achievement of net sales					$ 1,000,000,000