Quarterly report pursuant to Section 13 or 15(d)

Summary of Significant Accounting Policies (Tables)

Summary of Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2023

Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares Outstanding

For the periods presented, the following ordinary shares underlying the options, unvested restricted share units, warrants and the Exchangeable Notes have been excluded from the calculation because they would be anti-dilutive.


	Three and Six Months Ended
	June 30, 2023		June 30, 2022
Options to purchase ordinary shares		1,125,991		1,221,095
Unvested restricted share units		38,540		123,521
Warrants		480,186		480,186
Exchangeable Notes		1,386,255		1,252,517
Total		3,030,972		3,077,319

Schedule of Distribution of Total Operating Expenses by Geographical Area

The distribution of total operating expenses by geographical area was as follows:


	Three Months Ended June 30,				Six Months Ended June 30,
Operating expenses	2023		2022		2023		2022
Ireland	$	9,485	$	5,078	$	16,553	$	9,627
U.S.		1,336		2,966		2,776		5,777
Bermuda		1		6		23		19
Total	$	10,822	$	8,050	$	19,352	$	15,423

Schedule of Distribution of Long-Lived Assets by Geographical Area

The distribution of long-lived assets by geographical area was as follows:


Long-lived assets	June 30, 2023		December 31, 2022
Ireland	$	3,077	$	4,052
U.S.		257		303
Total	$	3,334	$	4,355