Quarterly report pursuant to Section 13 or 15(d)

Summary of Significant Accounting Policies (Tables)

Summary of Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2022

Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares Outstanding

For the periods presented, the following ordinary shares underlying the options, unvested restricted share units,

unvested performance restricted share units, warrants and the Exchangeable Notes have been excluded from the calculation because they would be anti-dilutive.


	Three Months Ended				Six Months Ended
	June 30, 2022		June 30, 2021		June 30, 2022		June 30, 2021
Options to purchase ordinary shares		18,316,699		—		18,316,699		14,065,145
Unvested restricted share units		1,852,877		—		1,852,877		1,315,328
Unvested performance restricted share units		—		—		—		407,000
Warrants		7,202,878		—		7,202,878		7,202,878
Exchangeable Notes		18,787,768		—		18,787,768		17,733,806
Total		46,160,222		—		46,160,222		40,724,157

Schedule of Distribution of Total Operating Expenses by Geographical Area

The distribution of total operating expenses by geographical area was as follows:


	Three Months Ended June 30,				Six Months Ended June 30,
Operating expenses	2022		2021		2022		2021
Ireland	$	5,078	$	4,192	$	9,627	$	8,110
U.S.		2,966		2,794		5,777		4,678
Bermuda		6		1		19		46
Total	$	8,050	$	6,987	$	15,423	$	12,834

Schedule of Distribution of Long-Lived Assets by Geographical Area

The distribution of long-lived assets by geographical area was as follows:


Long-lived assets	June 30, 2022		December 31, 2021
Ireland	$	5,404	$	7,601
U.S.		323		578
Total	$	5,727	$	8,179